PPolySim OS

Pharmacokinetics

Every drug rises, peaks, and clears. See the concentration curve form, and how half-life and dose keep it inside the therapeutic window.

PharmacokineticsLive

Controls

Presets

After a dose, drug concentration rises as it absorbs, then falls exponentially as the body clears it. The half-life sets the decline; the goal is to stay inside the therapeutic window — high enough to work, low enough to be safe. Educational tool, not medical advice.

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Data Inspector

Peak concentration12.02 mg/L
Time to peak1.9 h
Elimination rate ke0.173 /h

Governing equation

Reading this result: Absorption (ka 1.2/h) is much faster than elimination, so the drug reaches its peak quickly (about 1.9 h) and the curve then tracks the 4-hour half-life on the way down.

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How it works

A one-compartment model tracks plasma concentration as a drug absorbs and is eliminated. The half-life sets the exponential decline; dosing aims to keep levels above the minimum effective concentration but below the toxic threshold. Educational tool, not medical advice.

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Frequently asked questions

Is this pharmacokinetics simulator tool really free?
Yes. Pharmacokinetics runs entirely in your browser using your device's own compute, so local use is free forever. You only pay Compute Tokens if you scale a job to the cloud.
Do I need to install anything?
No. Everything runs client-side in a modern browser — no downloads, no license, no account required to start.
Can I save or share my simulation?
Create a free account to save projects, and use a shareable embed or minted DOI to publish a live, interactive version anywhere.
How accurate are the results?
The solver uses established numerical methods, but results are for research and educational purposes and should be validated against experiment or professional review before you rely on them.