PPolySim OS
Use case · powered by Sequence Alignment

Sequence Alignment for a synapse

Simulate a synapse live in your browser. This runs the real Sequence Alignment solver — adjust the inputs, watch it respond instantly, and export the result. No install, no account.

Sequence Alignment (Needleman-Wunsch)Live

Controls

Presets

The Needleman-Wunsch algorithm finds the optimal global alignment of two sequences by dynamic programming, filling a scoring matrix and tracing back the best path. It is the foundation of bioinformatics — comparing genes, proteins, and genomes. The heatmap shows the accumulated score matrix.

▶ Run in Python

Data Inspector

Alignment score0
Identity0%
Length0

Governing equation

Reading this result: Low similarity: only 0% of columns match (score 0). The optimal alignment leans on -2-penalty gaps and mismatches, so the sequences share little common structure.

Runs locally in your browser — free forever. Scale to the cloud when reality gets heavy.

or unlock everything with Pro →

About this simulation

The full Sequence Alignment tool models a synapse with the same numerics engineers and scientists use — running entirely client-side. Change any parameter and the result updates in real time, so you can build intuition, check a design, or teach the concept without spreadsheets or installs.

More you can do with Sequence Alignment

Other ways to simulate a synapse

Frequently asked questions

How do I simulate a synapse?
Open this page and use the live Sequence Alignment tool below — set your inputs and the simulation runs instantly in your browser using real numerics. No install, no account needed.
Is it free?
Yes. The simulation runs free in your browser. A one-time unlock or a Pro plan adds advanced parameters, saved presets, data import, and clean exports.
Can I use my own numbers?
Absolutely — every input is adjustable, and with data import you can drive a synapse from your own measurements.